How should I organize my scripts to fully support Unicode character encoding in gumps (like item/mobile description) and props? POL does have ...UC functions but do i need to have my script files encoding set to UTF8?

you mean this?

Yea

Care to elaborate on this? ;) I'm having the same problem, but with Polish characters in gumps.

We solved this problem on IRC channel with Asylum as i remember.
I use modified fonts.mul and unifont*.mul
Otherwise it doesn't work for me